Press Release

Proteograph utility is demonstrated as market interest continues to build with multiple studies underway

REDWOOD CITY, Calif., Nov. 08, 2022 (GLOBE NEWSWIRE) -- Seer, Inc. (Nasdaq: SEER), a life sciences company commercializing a disruptive new platform for proteomics, today reported financial results for the third quarter ended September 30, 2022.

“During the third quarter, we continued to see growing enthusiasm from our customers across a variety of applications, including discovery, translational and clinical research. We are seeing a growing commitment to the technology as customers around the world adopt the Proteograph Product Suite and conduct first-of-their kind studies that explore the proteome at a depth, resolution and scale that was not possible previously,” said Omid Farokhzad, Chief Executive Officer, President and Chair. “As we move ahead, we are excited about our opportunity, focused on our goals, and committed to enabling our customers' success.”  

Recent Highlights

• Revenue of $4.0 million for the third quarter 2022
• Published results in Advanced Materials highlighting how the combination of proteomic methods, nanoengineering and machine learning enables the capture of thousands of proteins
• Demonstrated utility of the technology to address different sample types, input volumes and species through customer proof-of-principle studies and presentations
• Increased utilization by pharma and academic users, who are accessing Seer’s technology through new projects with our Centers of Excellence partners
• Continued software and computation innovations with Seer’s latest deep peptide libraries, enabling up to a 50% increase in proteome depth and allowing for the identification of novel proteoforms
  

Third Quarter 2022 Financial Results

Revenue was $4.0 million for the three months ended September 30, 2022, as compared to $2.2 million for the three months ended September 30, 2021. The increase was primarily due to increased sales of the Proteograph Product Suite and its related products. Product-related revenue for the third quarter of 2022 was $3.9 million, including $1.3 million of related party revenue, and consisted of sales of SP100 instruments, consumable kits and platform evaluations.

Gross profit was $1.9 million and gross margin was 49% for the third quarter of 2022.

Operating expenses were $27.0 million for the third quarter of 2022, including $9.1 million of stock-based compensation, as compared to $19.6 million, including $6.8 million of stock-based compensation, for the corresponding prior year period. The increase in expenses was driven by increased employee compensation and other related expenses, including stock-based compensation, and increased expenses related to the expansion of the company’s facilities and other costs related to being a publicly traded company.

Net loss was $24.0 million for the third quarter of 2022, as compared to $18.4 million for the corresponding prior year period.

Cash, cash equivalents and investments were approximately $441.0 million as of September 30, 2022.

2022 Guidance

Seer continues to expect full year 2022 revenue to be in the range of $14.0 million to $16.0 million.

Webcast Information

Seer will host a conference call to discuss the third quarter financial results on Tuesday, November 8, 2022 at 1:30 pm Pacific Time / 4:30 pm Eastern Time. A webcast of the conference call can be accessed at http://investor.seer.bio. The webcast will be archived and available for replay for at least 90 days after the event.

About Seer

Seer™ is a life sciences company developing transformative products that open a new gateway to the proteome. Seer’s Proteograph™ Product Suite is an integrated solution that includes proprietary engineered nanoparticles, consumables, automation instrumentation and software to perform deep, unbiased proteomic analysis at scale in a matter of hours. Seer designed the Proteograph workflow to be efficient and easy to use, leveraging widely adopted laboratory instrumentation to provide a decentralized solution that can be incorporated by nearly any lab. Seer’s Proteograph Product Suite is for research use only and is not intended for diagnostic procedures. For more information, please visit www.seer.bio.

Forward Looking Statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, that reflect the Company’s current views with respect to certain current and future events and financial performance. Words such as “expects,” “anticipates,” “projects,” “intends,” “plans,” “believes,” “estimates,” variations of such words, and similar expressions are also intended to identify such forward-looking statements. Such forward-looking statements are based on the Company’s beliefs and assumptions and on information currently available to it on the date of this press release. Forward-looking statements may involve known and unknown risks, uncertainties and other factors that may cause the Company’s actual results, performance or achievements to be materially different from those expressed or implied by the forward-looking statements, including but not limited to statements regarding the Company’s outlook for fiscal year 2022. These and other risks are described more fully in the Company’s filings with the Securities and Exchange Commission (“SEC”), including the Company’s Quarterly Report on Form 10-Q, to be filed with the SEC, and other documents the Company subsequently files with the SEC from time to time. Except to the extent required by law, the Company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Investor Contact:
Carrie Mendivil
investor@seer.bio

Media Contact:
Karen Possemato
pr@seer.bio

Seer, Inc.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(In thousands, except share and per share amounts)
(Unaudited)

	Three Months Ended September 30,								Nine Months Ended September 30,
		2022				2021				2022				2021
Revenue:
Product	$	2,571			$	858			$	7,126			$	1,695
Service		68				500				204				500
Related party		1,316				787				3,494				1,167
Grant and other		—				10				64				189
Total revenue		3,955				2,155				10,888				3,551
Cost of revenue:
Product		1,371				574				4,674				1,078
Service		21				42				50				42
Related party		618				370				1,366				452
Total cost of revenue		2,010				986				6,090				1,572
Gross profit		1,945				1,169				4,798				1,979
Operating expenses:
Research and development		11,564				7,745				33,167				20,906
Selling, general and administrative		15,447				11,855				43,917				32,672
Total operating expenses		27,011				19,600				77,084				53,578
Loss from operations		(25,066	)			(18,431	)			(72,286	)			(51,599	)
Other income (expense):
Interest income		1,285				46				2,105				169
Other expense		(199	)			—				(260	)			—
Total other income		1,086				46				1,845				169
Net loss	$	(23,980	)		$	(18,385	)		$	(70,441	)		$	(51,430	)
Other comprehensive loss:
Unrealized gain (loss) on available-for-sale securities		420				26				(2,157	)			(62	)
Comprehensive loss	$	(23,560	)		$	(18,359	)		$	(72,598	)		$	(51,492	)
Net loss per share attributable to common stockholders, basic and diluted	$	(0.38	)		$	(0.30	)		$	(1.13	)		$	(0.85	)
Weighted-average common shares outstanding, basic and diluted		62,538,983				61,133,518				62,308,314				60,625,601

Seer, Inc.
CONDENSED CONSOLIDATED BALANCE SHEETS
(in thousands, except share and per share amounts)

	September 30,				December 31,
		2022				2021
	(unaudited)
ASSETS
Current assets:
Cash and cash equivalents	$	68,069			$	232,813
Short-term investments		367,995				167,261
Accounts receivable, net		4,537				2,495
Related party receivables		829				1,283
Other receivables		1,012				366
Inventory		5,916				4,145
Prepaid expenses and other current assets		2,113				3,336
Total current assets		450,471				411,699
Long-term investments		4,873				93,186
Operating lease right-of-use assets		27,465				20,142
Property and equipment, net		16,084				13,087
Restricted cash		524				524
Other assets		795				501
Total assets	$	500,212			$	539,139
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable	$	3,975			$	3,789
Accrued expenses		7,821				8,394
Deferred revenue		325				376
Operating lease liabilities, current		1,314				864
Other current liabilities		181				—
Total current liabilities		13,616				13,423
Operating lease liabilities, net of current portion		28,509				22,459
Other noncurrent liabilities		319				341
Total liabilities		42,444				36,223
Commitments and contingencies
Stockholders’ equity:
Preferred stock, $0.00001 par value; 5,000,000 shares authorized as of September 30, 2022 and December 31, 2021; zero shares issued and outstanding as of September 30, 2022 and December 31, 2021		—				—
Class A common stock, $0.00001 par value; 94,000,000 shares authorized as of September 30, 2022 and December 31, 2021; 58,591,785 and 57,493,005 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively		1				1
Class B common stock, $0.00001 par value; 6,000,000 shares authorized as of September 30, 2022 and December 31, 2021; 4,044,969 and 4,522,478 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively		—				—
Additional paid-in capital		657,431				629,981
Accumulated other comprehensive loss		(2,693	)			(536	)
Accumulated deficit		(196,971	)			(126,530	)
Total stockholders’ equity		457,768				502,916
Total liabilities and stockholders’ equity	$	500,212			$	539,139